Inhibition of Human Immunodeficiency Virus Type 1 (HIV-1) Replication by HIV-1-Based Lentivirus Vectors Expressing Transdominant Rev

Retrovirus vectors expressing transdominant-negative mutants of Rev (TdRev) inhibit human immunodeficiency virus type 1 (HIV-1) replication by preventing the nuclear export of unspliced viral transcripts, thus inhibiting the synthesis of Gag-Pol, Env, and genomic RNA. The use of HIV-1–based vectors...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Mautino, Mario R., Keiser, Nicholas, Morgan, Richard A.
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 2001
Matèries:	Gene Therapy
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114850/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11264348/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.8.3590-3599.2001
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