Stimulation of glycogenolysis in isolated hepatocytes by adenosine and one of its analogues is inhibited by caffeine.

The adenosine analogues 5'-(N-ethyl)carboxamidoadenosine (NECA) and N6-(phenylisopropyl)adenosine (PIA) activate glycogen phosphorylase 5-fold and 4.2-fold respectively in rat hepatocytes incubated in the absence of endogenous adenosine. Half-maximally effective concentrations are 0.5 microM fo...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Stanley, J C, Markovic, J, Gutknecht, A M, Lozeman, F J
Format: Artigo
Langue:Inglês
Publié: 1987
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148479/
https://ncbi.nlm.nih.gov/pubmed/3426562
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