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Desferrioxamine (Desferal) and superoxide free radicals. Formation of an enzyme-damaging nitroxide.

In neutral solutions, desferrioxamine (Desferal) can react with the superoxide free radical, O2.- (possibly through its protonated form HO2.), to form a relatively stable nitroxide free radical, which can have a half-life of approx. 10 min at room temperature. The formation of the radical can be lar...

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Detalhes bibliográficos
Main Authors: Davies, M J, Donkor, R, Dunster, C A, Gee, C A, Jonas, S, Willson, R L
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148337/
https://ncbi.nlm.nih.gov/pubmed/2825650
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