Infrequent Occurrence of Natural Mutations in the pp65(495–503) Epitope Sequence Presented by the HLA A∗0201 Allele among Human Cytomegalovirus Isolates

To determine if mutations of an immunodominant HLA-restricted cytomegalovirus (CMV) peptide sequence occur in nature, the sequence corresponding to the HLA A∗0201-specific peptide CMVpp65(495–503) was determined in 50 human CMV isolates. Rare mutations were detected; 6 of 50 were silent mutations at...

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Главные авторы: Zaia, John A., Gallez-Hawkins, Ghislaine, Li, Xiuli, Yao, Zhi-Qiang, Lomeli, Norma, Molinder, Karen, La Rosa, Corinna, Diamond, Don J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Pathogenesis and Immunity
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC114832/
https://ncbi.nlm.nih.gov/pubmed/11160752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2472-2474.2001
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