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Chemical modification of human alpha 1-proteinase inhibitor by tetranitromethane. Structure-function relationship.

Nitration of tyrosine residues of alpha 1-proteinase inhibitor (alpha 1-PI) by tetranitromethane yielded a product that maintained its inhibitory activity against trypsin but lost most of its inhibitory activity against elastase. Chemical analysis of the product showed that four out of the six tyros...

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Bibliografski detalji
Glavni autori: Mierzwa, S, Chan, S K
Format: Artigo
Jezik:Inglês
Izdano: 1987
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148237/
https://ncbi.nlm.nih.gov/pubmed/3499901
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