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Use of Helper-Free Replication-Defective Simian Immunodeficiency Virus-Based Vectors To Study Macrophage and T Tropism: Evidence for Distinct Levels of Restriction in Primary Macrophages and a T-Cell Line

Cell tropism of human and simian immunodeficiency viruses (HIV and SIV, respectively) is governed in part by interactions between the viral envelope protein and the cellular receptors. However, there is evidence that envelope-host cell interactions also affect postentry steps in viral replication. W...

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Detalhes bibliográficos
Main Authors: Kim, Steve S., You, Xue Juan, Harmon, Mary-Elizabeth, Overbaugh, Julie, Fan, Hung
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114812/
https://ncbi.nlm.nih.gov/pubmed/11160732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2288-2300.2001
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