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The behaviour of leucine aminopeptidase towards thionopeptides.

Thionoleucine S-anilide (Leut-anilide), Leut-Gly-OEt and Leut-Phe-OMe were synthesized and shown to be competitive inhibitors of leucine aminopeptidase from pig kidney. The kinetics of inhibition were determined in the presence of leucine 4-methylcoumarin-7-amide as substrate. Although the compounds...

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Main Authors: Beattie, R E, Elmore, D T, Williams, C H, Guthrie, D J
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148113/
https://ncbi.nlm.nih.gov/pubmed/3663153
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