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Down-regulation of protein kinase C is due to an increased rate of degradation.

The phorbol-ester-induced loss of protein kinase C that has been documented in many cell types appears to be a critical event in the generation of a cellular refractory state. We have investigated here the synthesis and degradation of the protein kinase C polypeptide in order to determine why its st...

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Detalhes bibliográficos
Main Authors: Young, S, Parker, P J, Ullrich, A, Stabel, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1148063/
https://ncbi.nlm.nih.gov/pubmed/3446191
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