Increased Readthrough Transcription across the Simian Virus 5 M-F Gene Junction Leads to Growth Defects and a Global Inhibition of Viral mRNA Synthesis

Recombinant simian virus 5 (rSV5) mutants containing substitutions in the M-F intergenic region were generated to determine the effect of increased readthrough transcription on the paramyxovirus growth cycle. We have previously shown, using an SV5 dicistronic minigenome, that replacement of the 22-b...

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הוצא לאור ב:	J Virol
Principais autores:	Parks, Griffith D., Ward, Kimberly R., Rassa, John C.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2001
נושאים:	Replication
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114805/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160725/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2213-2223.2001
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