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Single-Chain Antibody Displayed on a Recombinant Measles Virus Confers Entry through the Tumor-Associated Carcinoembryonic Antigen

To redirect the tropism of the vaccine strain of measles virus (MV), Edmonston B, to a targeted cell population, we displayed on the viral hemagglutinin (H) a single-chain antibody (scAb) specific for the tumor-associated carcinoembryonic antigen (CEA). We generated H fusion proteins with three form...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:J Virol
Ngā kaituhi matua: Hammond, Anthea L., Plemper, Richard K., Zhang, Jie, Schneider, Urs, Russell, Stephen J., Cattaneo, Roberto
Hōputu: Artigo
Reo:Inglês
I whakaputaina: American Society for Microbiology (ASM) 2001
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11160713/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.5.2087-2096.2001
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