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Effect of Intragenic Rearrangement and Changes in the 3′ Consensus Sequence on NSP1 Expression and Rotavirus Replication

The nonpolyadenylated mRNAs of rotavirus are templates for the synthesis of protein and the segmented double-stranded RNA (dsRNA) genome. During serial passage of simian SA11 rotaviruses in cell culture, two variants emerged with gene 5 dsRNAs containing large (1.1 and 0.5 kb) sequence duplications...

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Main Authors: Patton, John T., Taraporewala, Zenobia, Chen, Dayue, Chizhikov, Vladimir, Jones, Melinda, Elhelu, Azza, Collins, Megan, Kearney, Karen, Wagner, Mariam, Hoshino, Yasutaka, Gouvea, Vera
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114792/
https://ncbi.nlm.nih.gov/pubmed/11160712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.5.2076-2086.2001
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