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Plasmid-mediated trimethoprim-resistance in Staphylococcus aureus. Characterization of the first gram-positive plasmid dihydrofolate reductase (type S1).

The trimethoprim-resistance gene located on plasmid pSK1, originally identified in a multi-resistant Staphylococcus aureus from Australia, encodes the production of a dihydrofolate reductase (type S1), which confers a high degree of resistance to its host and is quite unlike any plasmid-encoded dihy...

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Main Authors: Young, H K, Skurray, R A, Amyes, S G
格式: Artigo
語言:Inglês
出版: 1987
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147852/
https://ncbi.nlm.nih.gov/pubmed/3606580
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