Rapid Appearance of Secondary Immune Responses and Protection from Acute CD4 Depletion after a Highly Pathogenic Immunodeficiency Virus Challenge in Macaques Vaccinated with a DNA Prime/Sendai Virus Vector Boost Regimen

Heterologous prime/boost regimens are AIDS vaccine candidates because of their potential for inducing cellular immune responses. Here, we have developed a prime/boost regimen leading to rapid control of highly pathogenic immunodeficiency virus infection in macaques. The strategy, priming by an env a...

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Autors principals: Matano, Tetsuro, Kano, Munehide, Nakamura, Hiromi, Takeda, Akiko, Nagai, Yoshiyuki
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114777/
https://ncbi.nlm.nih.gov/pubmed/11689672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11891-11896.2001
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