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RNase H Cleavage of the 5′ End of the Human Immunodeficiency Virus Type 1 Genome

The synthesis of retroviral DNA is initiated near the 5′ end of the RNA. DNA synthesis is transferred from the 5′ end to the 3′ end of viral RNA in an RNase H-dependent step. In the case of human immunodeficiency virus type 1 (HIV-1) (and certain other retroviruses that have complex secondary struct...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gao, Hong-Qiang, Sarafianos, Stefan G., Arnold, Edward, Hughes, Stephen H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114774/
https://ncbi.nlm.nih.gov/pubmed/11689669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11874-11880.2001
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