Increase in a specific cytochrome P-450 isoenzyme in the liver of congenitally jaundiced Gunn rats.

Congenitally jaundiced (jj) Gunn rats had a greater hepatic microsomal content of a cytochrome P-450 isoenzyme, P-450c, than did the non-jaundiced (Jj) rats. No differences in content of P-450b, P-450d and pregnenolone-16 alpha-carbonitrile-induced (PCN) P-450 were found between jj and Jj rats. This...

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Bibliographic Details
Main Authors: Kapitulnik, J, Hardwick, J P, Ostrow, J D, Webster, C C, Park, S S, Gelboin, H V
Format: Artigo
Language:Inglês
Published: 1987
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147698/
https://ncbi.nlm.nih.gov/pubmed/3593244
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