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Yeast phosphoglycerate kinase: investigation of catalytic function by site-directed mutagenesis.

A salt link buried in the domain interface of phosphoglycerate kinase has been implicated as being important in controlling the conformational transition from the open, or substrate-binding, to the closed, or catalytically competent, form of the enzyme. The residues contributing to the salt link are...

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Autors principals: Wilson, C A, Hardman, N, Fothergill-Gilmore, L A, Gamblin, S J, Watson, H C
Format: Artigo
Idioma:Inglês
Publicat: 1987
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147603/
https://ncbi.nlm.nih.gov/pubmed/3297036
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