The identification of a new cyclic nucleotide phosphodiesterase activity in human and guinea-pig cardiac ventricle. Implications for the mechanism of action of selective phosphodiesterase inhibitors.

Four cyclic nucleotide phosphodiesterase (PDE) activities were separated from low-speed supernatants of homogenates of human cardiac ventricle by DEAE-Sepharose chromatography, and designated PDE I-PDE IV in order of elution with an increasing salt gradient. PDE I was a Ca2+/calmodulin-stimulated ac...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Reeves, M L, Leigh, B K, England, P J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1987
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147593/
https://ncbi.nlm.nih.gov/pubmed/3036066
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