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The Retroviruses Human Immunodeficiency Virus Type 1 and Moloney Murine Leukemia Virus Adopt Radically Different Strategies To Regulate Promoter-Proximal Polyadenylation

Maximal gene expression in retroviruses requires that polyadenylation in the 5′ long terminal repeat (LTR) is suppressed. In human immunodeficiency virus type 1 (HIV-1) the promoter-proximal poly(A) site is blocked by interaction of U1 snRNP with the closely positioned major splice donor site (MSD)...

詳細記述

保存先:
書誌詳細
主要な著者: Furger, Andre, Monks, Joan, Proudfoot, Nick J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2001
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC114759/
https://ncbi.nlm.nih.gov/pubmed/11689654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11735-11746.2001
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