High-Dose Borna Disease Virus Infection Induces a Nucleoprotein-Specific Cytotoxic T-Lymphocyte Response and Prevention of Immunopathology

Experimental Borna disease virus (BDV) infection of rats and natural infection of horses and sheep leads to severe central nervous system disease based on immunopathological pathways. The virus replicates slowly, and the cellular immune response results in immunopathology. CD8(+) T cells exert effec...

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Bibliographic Details
Main Authors: Furrer, Esther, Bilzer, Thomas, Stitz, Lothar, Planz, Oliver
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC114756/
https://ncbi.nlm.nih.gov/pubmed/11689651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11700-11708.2001
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