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Effects of weakly basic amines on proteolytic processing and terminal glycosylation of secretory proteins in cultured rat hepatocytes.

We examined the effects of weakly basic amines on the secretion and post-translational modifications of secretory proteins in cultured rat hepatocytes. Weakly basic amines such as methylamine, chloroquine and NH4Cl strongly inhibited not only protein secretion, but also the proteolytic conversion of...

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Détails bibliographiques
Auteurs principaux: Oda, K, Koriyama, Y, Yamada, E, Ikehara, Y
Format: Artigo
Langue:Inglês
Publié: 1986
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147481/
https://ncbi.nlm.nih.gov/pubmed/3493770
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