A Cyclic Dodecapeptide–Multiple-Antigen Peptide Conjugate from the Undecapeptidyl Arch (from Arg(168) to Cys(178)) of Extracellular Loop 2 in CCR5 as a Novel Human Immunodeficiency Virus Type 1 Vaccine

A cyclic closed-chain dodecapeptide (cDDR5) mimicking the conformation-specific domain of CCR5 was prepared in which Gly-Asp, as a dipeptide forming a spacer arm, links the amino and carboxyl termini of the decapeptidyl linear chain (Arg(168) to Thr(177)) derived from the undecapeptidyl arch (UPA; A...

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Autores principales: Misumi, Shogo, Nakajima, Reina, Takamune, Nobutoki, Shoji, Shozo
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114748/
https://ncbi.nlm.nih.gov/pubmed/11689643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11614-11620.2001
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