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Abnormal regulation of insulin secretion in the genetically obese (ob/ob) mouse.

To determine whether the abnormal insulin-secretory activity encountered in obese mice is due to an anomaly in the production of cyclic AMP, islets of lean and obese mice were incubated with forskolin under various conditions. Our data show that, in addition to the well-known quantitative difference...

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Detalhes bibliográficos
Main Authors: Black, M, Heick, H M, Bégin-Heick, N
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1147215/
https://ncbi.nlm.nih.gov/pubmed/3026362
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