Unique Temperature-Sensitive Defect in Vaccinia Virus Morphogenesis Maps to a Single Nucleotide Substitution in the A30L Gene

Marker rescue experiments demonstrated that the genetic lesion of a previously isolated vaccinia virus temperature-sensitive mutant which forms multilayered envelope structures with lucent interiors and foci of viroplasm with dense centers mapped to the A30L open reading frame. A single base change,...

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Bibliografiske detaljer
Main Authors: Szajner, Patricia, Weisberg, Andrea S., Moss, Bernard
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114702/
https://ncbi.nlm.nih.gov/pubmed/11602762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.22.11222-11226.2001
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