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Identification of lysine at the active site of human 5-aminolaevulinate dehydratase.

Reduction of human 5-aminolaevulinate dehydratase with NaBH4 in the presence of 14C-labelled substrate led to complete loss of catalytic activity and to incorporation of label into the enzyme protein. By comparison with authentic lysyl-aminolaevulinic acid, prepared chemically, the modified active-s...

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Bibliographic Details
Main Authors: Gibbs, P N, Jordan, P M
Format: Artigo
Language:Inglês
Published: 1986
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1146860/
https://ncbi.nlm.nih.gov/pubmed/3092810
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