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Proteasome-Independent Disruption of PML Oncogenic Domains (PODs), but Not Covalent Modification by SUMO-1, Is Required for Human Cytomegalovirus Immediate-Early Protein IE1 To Inhibit PML-Mediated Transcriptional Repression

Human cytomegalovirus (HCMV) major immediate-early protein IE1 is an abundant 72-kDa nuclear phosphoprotein that is thought to play an important role in efficient triggering of the lytic cycle, especially at low multiplicity of infection. The best-known properties of IE1 at present are its transient...

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Udgivet i:J Virol
Principais autores: Xu, Yixun, Ahn, Jin-Hyun, Cheng, Mingfei, apRhys, Colette M., Chiou, Chuang-Jiun, Zong, Jianchao, Matunis, Michael J., Hayward, Gary S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2001
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114650/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11602710/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.22.10683-10695.2001
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