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Glycoprotein D-Independent Infectivity of Pseudorabies Virus Results in an Alteration of In Vivo Host Range and Correlates with Mutations in Glycoproteins B and H

Infection of cells by herpesviruses is initiated by the interaction of viral envelope glycoproteins with cellular receptors. In the alphaherpesvirus pseudorabies virus (PrV), the causative agent of Aujeszky's disease in pigs, the essential glycoprotein D (gD) mediates secondary attachment of vi...

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Autors principals: Schmidt, Jerg, Gerdts, Volker, Beyer, Jörg, Klupp, Barbara G., Mettenleiter, Thomas C.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC114580/
https://ncbi.nlm.nih.gov/pubmed/11581374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.21.10054-10064.2001
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