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Overexpression of Simian Virus 40 Small-T Antigen Blocks Centrosome Function and Mitotic Progression in Human Fibroblasts

Recombinant adenoviruses that express high levels of the simian virus 40 (SV40) small-t (ST) antigen have been used to study the requirement for ST to drive cell cycle proliferation of confluent human diploid fibroblasts. This occurs when either large-T (LT) antigen or serum is added to provide a se...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Gaillard, Stéphanie, Fahrbach, Kelly M., Parkati, Rajini, Rundell, Kathleen
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114552/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11559813/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.20.9799-9807.2001
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