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Molecular Determinants of Species Specificity in the Coronavirus Receptor Aminopeptidase N (CD13): Influence of N-Linked Glycosylation

Aminopeptidase N (APN), a 150-kDa metalloprotease also called CD13, serves as a receptor for serologically related coronaviruses of humans (human coronavirus 229E [HCoV-229E]), pigs, and cats. These virus-receptor interactions can be highly species specific; for example, the human coronavirus can us...

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Detalhes bibliográficos
Main Authors: Wentworth, David E., Holmes, Kathryn V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114546/
https://ncbi.nlm.nih.gov/pubmed/11559807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.20.9741-9752.2001
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