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Evidence that non-covalent forces, thiol and disulphide groups affect the structure and binding properties of the prolactin receptor on hepatocytes from pregnant rats.

Incubation of hepatocytes from pregnant rats with dithiothreitol decreased specific 125I-prolactin (125I-prl) binding to such cells by about 20% relative to control. This was not due to a non-specific effect of dithiothreitol on the cell membrane, since reduction also altered the binding of prl to s...

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Main Authors: Yamada, K, Donner, D B
格式: Artigo
語言:Inglês
出版: 1985
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144996/
https://ncbi.nlm.nih.gov/pubmed/2990446
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