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Downregulation of p56(lck) Tyrosine Kinase Activity in T Cells of Squirrel Monkeys (Saimiri sciureus) Correlates with the Nontransforming and Apathogenic Properties of Herpesvirus Saimiri in Its Natural Host
Herpesvirus saimiri is capable of transforming T lymphocytes of various primate species to stable growth in culture. The interaction of the T-cellular tyrosine kinase p56(lck) with the transformation-associated viral protein Tip has been shown before to activate the kinase and provides one model for...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC114492/ https://ncbi.nlm.nih.gov/pubmed/11533187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9252-9261.2001 |
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