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Mechanism of the inhibition of cholesterol biosynthesis by 6-fluoromevalonate.

6-Fluoromevalonate blocks the incorporation of mevalonic acid, but not that of isopentenyl pyrophosphate, into non-saponifiable lipids in a rat liver multienzyme system. With 3H-labelled 6-fluoromevalonate, it was found that 6-fluoromevalonate is converted to its phospho and pyrophospho derivatives...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Nave, J F, d'Orchymont, H, Ducep, J B, Piriou, F, Jung, M J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1985
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144833/
https://ncbi.nlm.nih.gov/pubmed/2986604
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