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Effect of cobalamin inactivation on folate-dependent transformylases involved in purine synthesis in rats.

N2O oxidizes and inactivates cob[I]alamin, and animals exposed in this way serve as models for cobalamin 'deficiency'. Such animals show a fall in activity of glycinamide ribotide transformylase and a rise in that of 5-amino-4-imidazolecarboxamide ribotide transformylase. The fall in glyci...

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Bibliografske podrobnosti
Main Authors: Deacon, R, Perry, J, Lumb, M, Chanarin, I
Format: Artigo
Jezik:Inglês
Izdano: 1985
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144809/
https://ncbi.nlm.nih.gov/pubmed/3994693
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