N-Oxidation of 4-chloroaniline by prostaglandin synthase. Redox cycling of radical intermediate(s).

4-Chloroaniline undergoes N-oxidation in ram seminal-vesicle microsomal preparations supplemented with arachidonic acid to yield N-(4-chlorophenyl)-hydroxylamine and 1-chloro-4-nitrosobenzene. H2O2 also supports metabolism of the amine substrate to the same organic-solvent-extractable products, sugg...

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Bibliographic Details
Main Authors: Golly, I, Hlavica, P
Format: Artigo
Language:Inglês
Published: 1985
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144780/
https://ncbi.nlm.nih.gov/pubmed/2985047
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