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A Novel Nonnucleoside Inhibitor Specifically Targets Cytomegalovirus DNA Maturation via the UL89 and UL56 Gene Products

3-Hydroxy-2,2-dimethyl-N-[4({[5-(dimethylamino)-1-naphthyl]sulfonyl}amino)-phenyl]propanamide (BAY 38-4766) is a novel selective nonnucleoside inhibitor of cytomegalovirus (CMV) replication with an excellent safety profile. This compound and structural analogues inhibit neither viral DNA synthesis n...

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Bibliográfalaš dieđut
Publikašuvnnas:J Virol
Váldodahkkit: Buerger, Iris, Reefschlaeger, Juergen, Bender, Wolfgang, Eckenberg, Peter, Popp, Andreas, Weber, Olaf, Graeper, Sascha, Klenk, Hans-Dieter, Ruebsamen-Waigmann, Helga, Hallenberger, Sabine
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: American Society for Microbiology (ASM) 2001
Fáttát:
Liŋkkat:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC114476/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11533171/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.75.19.9077-9086.2001
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