Interferon-Independent, Human Immunodeficiency Virus Type 1 gp120-Mediated Induction of CXCL10/IP-10 Gene Expression by Astrocytes In Vivo and In Vitro

The CXC chemokine gamma interferon (IFN-γ)-inducible protein CXCL10/IP-10 is markedly elevated in cerebrospinal fluid and brain of individuals infected with human immunodeficiency virus type 1 (HIV-1) and is implicated in the pathogenesis of HIV-associated dementia (HAD). To explore the possible rol...

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Detalhes bibliográficos
Main Authors: Asensio, Valérie C., Maier, Joachim, Milner, Richard, Boztug, Kaan, Kincaid, Carrie, Moulard, Maxime, Phillipson, Curtis, Lindsley, Kristen, Krucker, Thomas, Fox, Howard S., Campbell, Iain L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114435/
https://ncbi.nlm.nih.gov/pubmed/11435587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.7067-7077.2001
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