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Modification of hydroxymethylbilane synthase (porphobilinogen deaminase) by pyridoxal 5'-phosphate. Demonstration of an essential lysine residue.

When hydroxymethylbilane synthase (porphobilinogen deaminase) from Euglena gracilis is incubated with pyridoxal 5'-phosphate at pH 7.0 and 0 degree C, it rapidly loses part of its activity. The proportion of activity that remains decreases as the concentration of the modifier increases up to ap...

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Bibliografiske detaljer
Main Authors: Hart, G J, Leeper, F J, Battersby, A R
Format: Artigo
Sprog:Inglês
Udgivet: 1984
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144148/
https://ncbi.nlm.nih.gov/pubmed/6433896
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