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Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2.

Compactin, an inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase, decreased cholesterol synthesis in intact Hep G2 cells. However, after the inhibitor was washed away, the HMG-CoA-reductase activity determined in the cell homogenate was found to be increased. Also the high-affinity asso...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cohen, L H, Griffioen, M, Havekes, L, Schouten, D, van Hinsbergh, V, Kempen, H J
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1984
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1144140/
https://ncbi.nlm.nih.gov/pubmed/6089762
Etiketak: Etiketa erantsi
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