Molecular Basis for Cell Tropism of CXCR4-Dependent Human Immunodeficiency Virus Type 1 Isolates

Laboratory isolates of human immunodeficiency virus type 1 (HIV-1) that utilize CXCR4 as a coreceptor infect primary human macrophages inefficiently even though these express a low but detectable level of cell surface CXCR4. In contrast, infection of primary macrophages by primary CXCR4-tropic HIV-1...

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Autores principales: Tokunaga, Kenzo, Greenberg, Michael L., Morse, Michael A., Cumming, R. Ian, Lyerly, H. Kim, Cullen, Bryan R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
Virus-Cell Interactions
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC114404/
https://ncbi.nlm.nih.gov/pubmed/11435556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.15.6776-6785.2001
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