Population Genetic Analysis of the Protease Locus of Human Immunodeficiency Virus Type 1 Quasispecies Undergoing Drug Selection, Using a Denaturing Gradient-Heteroduplex Tracking Assay

Monitoring the evolution of human immunodeficiency virus type 1 (HIV-1) drug resistance requires measuring the frequency of closely related genetic variants making up the complex viral quasispecies found in vivo. In order to resolve both major and minor (≥2%) protease gene variants differing by one...

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Bibliografiska uppgifter
Huvudupphovsmän: Doukhan, Laurence, Delwart, Eric
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2001
Ämnen:
Recombination and Evolution
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC114399/
https://ncbi.nlm.nih.gov/pubmed/11413343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6729-6736.2001
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