Plasmacytoid Dendritic Cells Are Highly Susceptible to Human Immunodeficiency Virus Type 1 Infection and Release Infectious Virus

Plasmacytoid dendritic cells (pcDC) and myeloid dendritic cells (myDC) are shown to express CD4 and low levels of CCR5 and CXCR4, but only myDC express DC SIGN, a C-type lectin that binds human immunodeficiency virus but does not mediate virus entry. Both DC types were more susceptible to infection...

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Detalhes bibliográficos
Main Authors: Patterson, Steven, Rae, Aaron, Hockey, Nicola, Gilmour, Jill, Gotch, Frances
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114396/
https://ncbi.nlm.nih.gov/pubmed/11413340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6710-6713.2001
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