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Methylphenidate improves prefrontal cortical cognitive function through α2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder

BACKGROUND: Methylphenidate (MPH) is the classic treatment for Attention Deficit Hyperactivity Disorder (ADHD), yet the mechanisms underlying its therapeutic actions remain unclear. Recent studies have identified an oral, MPH dose regimen which when given to rats produces drug plasma levels similar...

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Detalhes bibliográficos
Main Authors: Arnsten, Amy FT, Dudley, Anne G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143775/
https://ncbi.nlm.nih.gov/pubmed/15916700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-1-2
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