Methylphenidate improves prefrontal cortical cognitive function through α2 adrenoceptor and dopamine D1 receptor actions: Relevance to therapeutic effects in Attention Deficit Hyperactivity Disorder

BACKGROUND: Methylphenidate (MPH) is the classic treatment for Attention Deficit Hyperactivity Disorder (ADHD), yet the mechanisms underlying its therapeutic actions remain unclear. Recent studies have identified an oral, MPH dose regimen which when given to rats produces drug plasma levels similar...

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Hlavní autoři: Arnsten, Amy FT, Dudley, Anne G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143775/
https://ncbi.nlm.nih.gov/pubmed/15916700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-9081-1-2
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