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Replication of Phenotypically Mixed Human Immunodeficiency Virus Type 1 Virions Containing Catalytically Active and Catalytically Inactive Reverse Transcriptase

The amount of excess polymerase and RNase H activity in human immunodeficiency virus type 1 virions was measured by using vectors that undergo a single round of replication. Vectors containing wild-type reverse transcriptase (RT), vectors encoding the D110E mutation to inactivate polymerase, and vec...

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Main Authors: Julias, John G., Ferris, Andrea L., Boyer, Paul L., Hughes, Stephen H.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC114377/
https://ncbi.nlm.nih.gov/pubmed/11413321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6537-6546.2001
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