A Small Interfering RNA Targeting Coxsackievirus B3 Protects Permissive HeLa Cells from Viral Challenge

We examined the ability of small interfering RNAs (siRNAs) to disrupt infection by coxsackievirus B3 (CVB3). The incorporation of siRNAs dramatically decreased cell death in permissive HeLa cells in parallel with a reduction in viral replication. Three of four siRNAs had potent anti-CVB3 activity. T...

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Bibliografiske detaljer
Main Authors: Ahn, Jeonghyun, Jun, Eun Seok, Lee, Hui Sun, Yoon, Seung Yong, Kim, DongHou, Joo, Chul-Hyun, Kim, Yoo Kyum, Lee, Heuiran
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2005
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143761/
https://ncbi.nlm.nih.gov/pubmed/15956603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8620-8624.2005
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