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Interruptions in gene expression drive highly expressed operons to the leading strand of DNA replication

In bacteria, most genes are on the leading strand of replication, a phenomenon attributed to collisions between the DNA and RNA polymerases. In Escherichia coli, these collisions slow the movement of the replication fork through actively transcribed genes only if they are coded on the lagging strand...

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Detalhes bibliográficos
Main Authors: Price, Morgan N., Alm, Eric J., Arkin, Adam P.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1143696/
https://ncbi.nlm.nih.gov/pubmed/15942025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki638
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