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Repression of Vaccinia Virus Holliday Junction Resolvase Inhibits Processing of Viral DNA into Unit-Length Genomes

The vaccinia virus A22R gene encodes a protein that is homologous to the bacterial enzyme RuvC and specifically cleaves and resolves four-way DNA Holliday junctions into linear duplex products. To investigate the role of the vaccinia virus Holliday junction resolvase during an infection, we construc...

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Detalles Bibliográficos
Main Authors: Garcia, Alonzo D., Moss, Bernard
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC114369/
https://ncbi.nlm.nih.gov/pubmed/11413313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6460-6471.2001
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