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A case-control study of the HER2 Ile655Val polymorphism in relation to risk of invasive breast cancer
BACKGROUND: Overexpression of the HER2 proto-oncogene in human cancer cells has been associated with a poor prognosis, and survival improves with therapy targeting the HER2 gene. Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HE...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143556/ https://ncbi.nlm.nih.gov/pubmed/15987431 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1004 |
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