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An Amino Acid Substitution in the Coding Region of the E2 Glycoprotein Adapts Ross River Virus To Utilize Heparan Sulfate as an Attachment Moiety

Passage of Ross River virus strain NB5092 in avian cells has been previously shown to select for virus variants that have enhanced replication in these cells. Sequencing of these variants identified two independent sites that might be responsible for the phenotype. We now demonstrate, using a molecu...

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Main Authors: Heil, Marintha L., Albee, Alison, Strauss, James H., Kuhn, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2001
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC114352/
https://ncbi.nlm.nih.gov/pubmed/11413296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.14.6303-6309.2001
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