Free Major Histocompatibility Complex Class I Heavy Chain Is Preferentially Targeted for Degradation by Human T-Cell Leukemia/Lymphotropic Virus Type 1 p12(I) Protein

Human T-cell leukemia virus type 1 (HTLV-1) establishes a persistent infection in the host despite a vigorous virus-specific immune response. Here we demonstrate that an HTLV-1-encoded protein, p12(I), resides in the endoplasmic reticulum (ER) and Golgi and physically binds to the free human major h...

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Detalhes bibliográficos
Main Authors: Johnson, Julie M., Nicot, Christophe, Fullen, Jake, Ciminale, Vincenzo, Casareto, Luca, Mulloy, James C., Jacobson, Steve, Franchini, Genoveffa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114324/
https://ncbi.nlm.nih.gov/pubmed/11390610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.6086-6094.2001
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