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Attrition of Bystander CD8 T Cells during Virus-Induced T-Cell and Interferon Responses

Experiments designed to distinguish virus-specific from non-virus-specific T cells showed that bystander T cells underwent apoptosis and substantial attrition in the wake of a strong T-cell response. Memory CD8 T cells (CD8(+) CD44(hi)) were most affected. During acute viral infection, transgenic T...

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Detalhes bibliográficos
Main Authors: McNally, James M., Zarozinski, Christopher C., Lin, Meei-Yun, Brehm, Michael A., Chen, Hong D., Welsh, Raymond M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114312/
https://ncbi.nlm.nih.gov/pubmed/11390598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5965-5976.2001
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