Theiler's Murine Encephalomyelitis Virus Induces Apoptosis in Gamma Interferon-Activated M1 Differentiated Myelomonocytic Cells through a Mechanism Involving Tumor Necrosis Factor Alpha (TNF-α) and TNF-α-Related Apoptosis-Inducing Ligand

Infection of susceptible mice with the low-neurovirulence Theiler's murine encephalomyelitis virus strain BeAn results in an inflammatory demyelinating disease similar to multiple sclerosis. While the majority of virus antigen is detected in central nervous system macrophages (Mφs), few infiltr...

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Main Authors: Jelachich, Mary Lou, Lipton, Howard L.
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2001
נושאים:
Pathogenesis and Immunity
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC114308/
https://ncbi.nlm.nih.gov/pubmed/11390594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.13.5930-5938.2001
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